The ACSM2A Polyclonal Antibody (CAB15563) is a valuable tool for researchers studying ACSM2A, a key protein involved in cellular energy metabolism and lipid metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples and is validated for use in Western blotting applications.ACSM2A, also known as Acyl-CoA synthetase medium-chain family member 2A, plays a crucial role in fatty acid metabolism by catalyzing the formation of acyl-CoA from medium-chain fatty acids. Dysregulation of ACSM2A has been linked to various metabolic disorders, making it a target of interest in research related to obesity, diabetes, and cardiovascular diseases.
By utilizing the ACSM2A Polyclonal Antibody, researchers can investigate the expression levels and localization of ACSM2A in different cell types and tissues, shedding light on its function and potential therapeutic implications. This antibody provides a valuable tool for advancing our understanding of ACSM2A's role in metabolic pathways and its impact on human health.
Product Name:
ACSM2A Rabbit Polyclonal Antibody
SKU:
CAB15563
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 418-577 of human ACSM2A (NP_001295101.1).
This gene encodes a mitochondrial acyl-coenzyme A synthetase that is specific for medium chain fatty acids. These enzymes catalyze fatty acid activation, the first step of fatty acid metabolism, through the transfer of acyl-CoA. These enzymes also participate in the glycine conjugation pathway in the detoxification of xenobiotics such as benzoate and ibuprofen. Expression levels of this gene in the kidney may be correlated with kidney function. This gene and its paralog ACSM2B (Gene ID: 348158), both present on chromosome 16, likely arose from a chromosomal duplication event.
Purification Method:
Affinity purification
Gene ID:
123876
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACSM2A Rabbit pAb (CAB15563) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
