ACSL5 Rabbit Polyclonal Antibody (CAB1270)
- SKU:
- CAB1270
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ACSL5 Rabbit Polyclonal Antibody |
SKU: | CAB1270 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-739 of human ACSL5 (NP_057318.2). |
Sequence: | GQTE CTGG CTFT LPGD WTSG HVGV PLAC NYVK LEDV ADMN YFTV NNEG EVCI KGTN VFKG YLKD PEKT QEAL DSDG WLHT GDIG RWLP NGTL KIID RKKN IFKL AQGE YIAP EKIE NIYN RSQP VLQI FVHG ESLR SSLV GVVV PDTD VLPS FAAK LGVK GSFE ELCQ NQVV REAI LEDL QKIG KESG LKTF EQVK AIFL HPEP FSIE NGLL TPTL KAKR GELS KYFR TQID SLYE HIQD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ACS2; ACS5; FACL5; ACSL5 |
Positive Sample: | HepG2,HL-60,Mouse liver,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum, Endoplasmic reticulum membrane, Mitochondrion, Mitochondrion outer membrane, Single-pass type III membrane protein. |
Calculated MW: | 76kDa |
Observed MW: | 70-76kDa |
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 51703 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |