ACSL4 Rabbit Polyclonal Antibody (CAB6826)
- SKU:
- CAB6826
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ACSL4 Rabbit Polyclonal Antibody |
SKU: | CAB6826 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-321 of human ACSL4 (NP_075266.1?). |
Sequence: | MAKR IKAK PTSD KPGS PYRS VTHF DSLA VIDI PGAD TLDK LFDH AVSK FGKK DSLG TREI LSEE NEMQ PNGK VFKK LILG NYKW MNYL EVNR RVNN FGSG LTAL GLKP KNTI AIFC ETRA EWMI AAQT CFKY NFPL VTLY ATLG KEAV VHGL NESE ASYL ITSV ELLE SKLK TALL DISC VKHI IYVD NKAI NKAE YPEG FEIH SMQS VEEL GSNP ENLG IPPS RPTP SDMA IVMY TSGS TGRP KGVM MHHS NLIA GMTG QCER IPGL GPKD TYIG YLPL |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsIHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ACS4; FACL4; LACS4; MRX63; MRX68; XLID63; ACSL4 |
Positive Sample: | HepG2,Hep G2 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein. |
Calculated MW: | 79kDa |
Observed MW: | 79kDa/74kDa |
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 2182 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |