The ACSL3 Polyclonal Antibody (CAB11679) is a valuable tool for researchers studying the Acyl-CoA Synthetase Long Chain Family Member 3 (ACSL3) protein. ACSL3 is an enzyme involved in lipid metabolism and has been implicated in various diseases, including cancer and metabolic disorders. This antibody is raised in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications.By binding to ACSL3, this antibody enables the detection and analysis of the protein in different cell types, providing researchers with insights into its role in cellular processes.
The ACSL3 Polyclonal Antibody is essential for studies in lipid metabolism, cancer biology, and metabolic diseases, as understanding the function of ACSL3 is crucial for developing targeted therapies for these conditions.Overall, the ACSL3 Polyclonal Antibody is a reliable tool for researchers investigating the role of ACSL3 in various diseases and biological processes, ultimately contributing to advancements in the fields of cancer research and metabolic disorders.
Product Name:
ACSL3 Rabbit Polyclonal Antibody
SKU:
CAB11679
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 621-720 of human ACSL3 (NP_004448.2).
Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein.
Calculated MW:
80kDa
Observed MW:
76kDa
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2181
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACSL3 Rabbit pAb (CAB11679) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
