The ACSF3 Polyclonal Antibody (CAB13769) is a powerful tool for researchers studying ACSF3, a key enzyme involved in fatty acid metabolism. Produced in rabbits, this antibody has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ACSF3 protein, this antibody enables precise detection and analysis of ACSF3 expression in various cell types, making it ideal for investigations in metabolic research and lipid metabolism studies.
ACSF3, also known as Acyl-CoA synthetase family member 3, plays a crucial role in converting fatty acids into their active form for various metabolic processes. Understanding the function of ACSF3 is vital for uncovering its involvement in metabolic diseases such as obesity, diabetes, and lipid storage disorders. By using the ACSF3 Polyclonal Antibody, researchers can explore the mechanisms underlying fatty acid metabolism and potentially develop targeted therapies for metabolic conditions.
Product Name:
ACSF3 Rabbit Polyclonal Antibody
SKU:
CAB13769
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-450 of human ACSF3 (NP_001230208.1).
This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
197322
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACSF3 Rabbit pAb (CAB13769) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
