The ACP5 Polyclonal Antibody (CAB16338) is a powerful tool for researchers studying ACP5, a key enzyme involved in bone resorption and skeletal development. This antibody, produced in rabbits, has high specificity for human samples and has been rigorously validated for use in Western blot applications. By targeting the ACP5 protein, researchers can effectively detect and analyze its expression in a variety of cell types, making it an invaluable tool for studies in bone biology, osteoporosis, and other skeletal disorders.
ACP5, also known as tartrate-resistant acid phosphatase type 5, is crucial for bone remodeling and plays a vital role in maintaining skeletal health. Dysregulation of ACP5 activity has been linked to conditions such as osteoporosis, Paget's disease, and bone metastasis in cancer. By gaining a better understanding of ACP5 function, researchers can develop targeted therapies to treat or prevent these debilitating conditions, ultimately improving the quality of life for patients affected by skeletal disorders.
Product Name:
ACP5 Rabbit Polyclonal Antibody
SKU:
CAB16338
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 76-325 of human ACP5 (NP_001602.1).
This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate.
Purification Method:
Affinity purification
Gene ID:
54
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using ACP5 Rabbit pAb (CAB16338) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
