ACOX1 Rabbit Polyclonal Antibody (CAB8091)
- SKU:
- CAB8091
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ACOX1 Rabbit Polyclonal Antibody |
SKU: | CAB8091 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACOX1 (NP_004026.2). |
Sequence: | MNPD LRRE RDSA SFNP ELLT HILD GSPE KTRR RREI ENMI LNDP DFQH EDLN FLTR SQRY EVAV RKSA IMVK KMRE FGIA DPDE IMWF KNFV HRGR PEPL DLHL GMFL PTLL HQAT AEQQ ERFF MPAW NLEI IGTY AQTE MGHG THLR GLET TATY DPET QEFI LNSP TVTS IKWW PGGL GKTS NHAI VLAQ LITK GKCY GLHA FIVP IREI GTHK PLPG ITVG DIGP KFGY DEID NGYL KMDN HRIP RENM LMKY AQVK PDGT YVKP LS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Synonyms: | AOX; ACOX; SCOX; MITCH; PALMCOX; ACOX1 |
Positive Sample: | Mouse liver,Mouse kidney,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Peroxisome. |
Calculated MW: | 74kDa |
Observed MW: | 74kDa/50kDa |
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 51 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |