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ACOT11 Monoclonal Antibody [PJ4B2AT] (CPAB0160)

SKU:
CPAB0160
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PJ4B2AT
Applications:
WB
ELISA
IHC
$179
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Description

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ACOT11 Monoclonal Antibody [PJ4B2AT] (CPAB0160)

The ACOT11 Polyclonal Antibody (CPAB0160) is a valuable tool for researchers studying ACOT11, an enzyme involved in lipid metabolism and energy production. This antibody, developed in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the ACOT11 protein, this antibody allows for detection and analysis in various cell types, making it ideal for investigations in the fields of metabolism, cellular energy homeostasis, and fatty acid oxidation.ACOT11, also known as acyl-CoA thioesterase 11, plays a crucial role in the breakdown of fatty acids and the regulation of cellular energy balance.

Dysregulation of ACOT11 has been linked to metabolic disorders, such as obesity and insulin resistance, making it a promising target for research aimed at understanding and treating these conditions. By studying the function of ACOT11, researchers can gain insights into lipid metabolism and energy regulation, with potential implications for the development of novel therapeutic strategies.

Product Name:ACOT11 Antibody
Product Sku:CPAB0160
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ACOT11 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACOT11 amino acids 19-25 purified from Ecoli.
Clone:PJ4B2AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:ACOT11 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse ACOT11 has been linked to obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice.
Synonyms:Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, Acyl-CoA thioester hydrolase 11, Brown fat-inducible thioesterase, BFIT, Adipose-associated thioesterase, ACOT11, BFIT, KIAA0707, THEA, BFIT1, BFIT2, THEM1, STARD14.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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