The Aconitase 2 Rabbit Monoclonal Antibody (CAB4524) is a highly specific research tool designed for studying the protein aconitase 2. This antibody, generated in rabbits, has been validated for use in various applications such as Western blotting and immunofluorescence.Aconitase 2 is an enzyme involved in the citric acid cycle, playing a crucial role in energy production within the mitochondria. Dysregulation of aconitase 2 has been linked to various diseases, including cancer and neurodegenerative disorders. By using this antibody, researchers can investigate the expression and localization of aconitase 2 in different cell types and tissues, providing valuable insights into its function and potential therapeutic targets.
With its high reactivity and specificity for human samples, the Aconitase 2 Rabbit Monoclonal Antibody (CAB4524) is an essential tool for research in biochemistry, cell biology, and disease mechanisms related to mitochondrial dysfunction. It offers a reliable and accurate method for studying aconitase 2 and its role in cellular metabolism and disease progression.
Product Name:
Aconitase 2 (ACO2) Rabbit Monoclonal Antibody
SKU:
CAB4524
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human Aconitase 2 (ACO2) (Q99798).
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
Purification Method:
Affinity purification
Gene ID:
50
Clone Number:
ARC1072
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Aconitase 2 (ACO2) (ACO2) Rabbit mAb (CAB4524) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
