The ACM2 Rabbit Monoclonal Antibody (CAB5154) is a cutting-edge tool for researchers studying ACM2, a protein involved in cell signaling pathways and implicated in various diseases. This antibody, produced in rabbits, has high specificity and sensitivity for detecting ACM2 in human samples, making it ideal for use in research applications such as immunohistochemistry and flow cytometry.ACM2, also known as adrenomedullin receptor, is a key player in regulating vascular tone, cell growth, and inflammation. Dysregulation of ACM2 signaling has been linked to conditions such as cardiovascular disease, cancer, and inflammation-related disorders.
By using this antibody to study ACM2 expression and function, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets.Overall, the ACM2 Rabbit Monoclonal Antibody (CAB5154) is a valuable tool for researchers seeking to understand the role of ACM2 in health and disease. Its high quality and reliability make it a trusted reagent for studies in molecular biology, pharmacology, and beyond.
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
1129
Clone Number:
ARC1225
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Muscarinic AChR M2 (Muscarinic AChR M2 (ACM2)) Rabbit mAb (CAB5154) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
