Muscarinic AChR M2 (ACM2) Rabbit Monoclonal Antibody (CAB5154)
- SKU:
- CAB5154
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Muscarinic AChR M2 (ACM2) Rabbit Monoclonal Antibody |
SKU: | CAB5154 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Muscarinic AChR M2 (ACM2) (P08172). |
Sequence: | LALD YVVS NASV MNLL IISF DRYF CVTK PLTY PVKR TTKM AGMM IAAA WVLS FILW APAI LFWQ FIVG VRTV EDGE CYIQ FFSN AAVT FGTA IAAF YLPV I |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HM2; Muscarinic AChR M2 (ACM2) |
Positive Sample: | SH-SY5Y,U-251MG,U-87MG,Mouse lung,Mouse testis,Mouse brain,Rat testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1129 |
Clone Number: | ARC1225 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |