The ACHE Antibody (PAC061446) is a polyclonal antibody designed for research involving acetylcholinesterase (ACHE), a crucial enzyme involved in the breakdown of the neurotransmitter acetylcholine. The antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in immunohistochemistry and other research applications.ACHE is involved in the regulation of cholinergic neurotransmission and is important for cognitive function and muscle movement. Dysregulation of ACHE activity has been implicated in various neurological disorders, including Alzheimer's disease and myasthenia gravis.
Understanding ACHE function and activity is essential for developing new therapies for these conditions.This antibody specifically binds to the ACHE protein, allowing for the detection and analysis of ACHE expression in various biological samples. Its high reactivity and specificity make it a valuable tool for researchers studying the role of ACHE in health and disease.
Antibody Name:
ache Antibody (PACO61446)
Antibody SKU:
PACO61446
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Zebrafish
Immunogen:
Recombinant Zebrafish Acetylcholinesterase protein (37-155AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: ache antibody at 2.3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 kDa. Observed band size: 38 kDa.
Background:
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
Synonyms:
Acetylcholinesterase, AChE, ache
UniProt Protein Function:
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
