Ku70 Rabbit Polyclonal Antibody (CAB0883)
- SKU:
- CAB0883
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Ku70 Rabbit Polyclonal Antibody |
SKU: | CAB0883 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 408-609 of human Ku70 (NP_001460.1). |
Sequence: | PYFV ALVP QEEE LDDQ KIQV TPPG FQLV FLPF ADDK RKMP FTEK IMAT PEQV GKMK AIVE KLRF TYRS DSFE NPVL QQHF RNLE ALAL DLME PEQA VDLT LPKV EAMN KRLG SLVD EFKE LVYP PDYN PEGK VTKR KHDN EGSG SKRP KVEY SEEE LKTH ISKG TLGK FTVP MLKE ACRA YGLK SGLK KQEL LEAL TKHF QD |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1; Ku70 |
Positive Sample: | SKOV3,COS7,SW480,HeLa,Mouse brain,Mouse liver,Mouse skeletal muscle,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 70kDa |
Observed MW: | 70kDa |
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Purification Method: | Affinity purification |
Gene ID: | 2547 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |