Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 Polyclonal Antibody (CAB21295)
- SKU:
- CAB21295
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 Polyclonal Antibody |
SKU: | CAB21295 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | A synthetic acetylated peptide around K4 & K27 of human Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 (NP_003520.1). |
Sequence: | TKQT ARKS TGGK APRK QLAT KAAR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A; Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 |
Positive Sample: | HeLa treated by TSA,NIH/3T3 treated by TSA,C6 treated by TSA,H3 protein |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 15kDa |
Observed MW: | 17kDa |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Purification Method: | Affinity purification |
Gene ID: | 8290/8350 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |