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Acetyl-HIST1H1B (K48) Antibody (PACO65063)

SKU:
PACO65063
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
$383
Frequently bought together:

Description

Acetyl-HIST1H1B (K48) Antibody (PACO65063)

The Acetyl-Hist1H1B (K48) Antibody (PAC065063) is a valuable tool for researchers studying acetylation of the histone protein Hist1H1B at the lysine 48 residue. This antibody, produced in rabbits, shows high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.Histone acetylation plays a crucial role in chromatin remodeling and gene expression regulation, with lysine 48 of Hist1H1B being a key site of modification. By targeting this specific acetylation site, researchers can gain insights into the epigenetic regulation of gene expression and its implications in various biological processes.

This antibody enables the detection and analysis of Hist1H1B acetylation in a variety of cell types, making it a valuable tool for studies in epigenetics, gene regulation, and cancer research. Understanding the role of acetylation at this specific site can provide valuable information for developing targeted therapies for diseases related to aberrant gene expression and chromatin remodeling.

Product Name:Acetyl-HIST1H1B (K48) Antibody
Product Code:PACO65063
Size:50µL
Target Names:HIST1H1B
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H1.5 protein (46-58aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5
Uniprot ID:P16401
Background:Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Research Area:Epigenetics and Nuclear Signaling

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