ACD Rabbit Polyclonal Antibody (CAB12177)
- SKU:
- CAB12177
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ACD Rabbit Polyclonal Antibody |
SKU: | CAB12177 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1). |
Sequence: | MPGR CQSD AAMR VNGP ASRA PAGW TSGS LHTG PRAG RPRA QARG VRGR GLLL RPRP AKEL PLPR KGGA WAPA GNPG PLHP LGVA VGMA GSGR LVLR PWIR ELIL GSET PSSP RAGQ LLEV LQDA EAAV AGPS HAPD TSDV GATL LVSD GTHS VRCL VTRE ALDT SDWE EKEF GFRG TEGR LLLL QDCG VHVQ VAEG GAPA EFYL QVDR FSLL PTEQ PRLR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PIP1; PTOP; TPP1; TINT1; ACD |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, telomere. |
Calculated MW: | 49kDa |
Observed MW: | 58kDa |
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Purification Method: | Affinity purification |
Gene ID: | 65057 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |