The ACBD5 Polyclonal Antibody (CAB10595) is designed for research involving ACBD5, a protein involved in lipid metabolism and the formation of lipid droplets in cells. The antibody, raised in rabbits, is highly specific for detecting ACBD5 in human samples and is validated for use in various applications such as Western blot and immunohistochemistry.ACBD5, also known as Acyl-CoA Binding Domain 5, plays a critical role in the regulation of lipid metabolism and storage within cells. Its importance in lipid droplet formation and lipid trafficking pathways makes it a key target for studying metabolic disorders, obesity, and fatty liver disease.
Understanding the functions of ACBD5 can provide insights into the mechanisms underlying these conditions and may lead to the development of new therapies targeting lipid metabolism.Overall, the ACBD5 Polyclonal Antibody is a valuable tool for researchers studying lipid metabolism, lipid droplet biology, and related disorders. Its high specificity and reliability make it an essential component for experiments aimed at unraveling the complexities of lipid homeostasis in health and disease.
Product Name:
ACBD5 Rabbit Polyclonal Antibody
SKU:
CAB10595
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 170-440 of human ACBD5 (NP_663736.2).
This gene encodes a member of the acyl-Coenzyme A binding protein family, known to function in the transport and distribution of long chain acyl-Coenzyme A in cells. This gene may play a role in the differentiation of megakaryocytes and formation of platelets. A related protein in yeast is involved in autophagy of peroxisomes. A mutation in this gene has been associated with autosomal dominant thrombocytopenia. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
91452
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACBD5 antibody (CAB10595) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
