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ACAT2 Monoclonal Antibody [PAT55D5AT] (CPAB0195)

SKU:
CPAB0195
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
€149
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Description

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ACAT2 Monoclonal Antibody [PAT55D5AT] (CPAB0195)

The ACAT2 Polyclonal Antibody (CPAB0195) is a vital tool for researchers studying ACAT2, an enzyme involved in cholesterol metabolism and lipid droplet formation. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of ACAT2 protein expression in various cell types.ACAT2 is a key player in lipid metabolism, particularly in the liver and intestines, where it is involved in the biosynthesis of cholesterol esters. Dysregulation of ACAT2 activity has been linked to a variety of metabolic disorders, including atherosclerosis and fatty liver disease, making it a promising target for therapeutic interventions aimed at modulating lipid homeostasis.

By utilizing the ACAT2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of ACAT2 in normal and disease states, paving the way for the development of novel treatments for lipid-related disorders. Its versatility and specificity make it an essential tool for studies in metabolic diseases and lipid biology.

Product Name:ACAT2 Antibody
Product Sku:CPAB0195
Size:5μg
Host Species:Mouse IgG2b
Immunogen:Anti-human ACAT2 mAb, clone PAT55D5AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACAT2 protein 1-397 amino acids purified from Ecoli.
Clone:PAT55D5AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:ACAT2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:ACAT2 enzyme participates in lipid metabolism. ACAT2 takes part in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. ACAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. ACAT2 deficiency contributes to severe mental retardation and hypotonus.
Synonyms:Acetyl-CoA acetyltransferase cytosolic, Cytosolic acetoacetyl-CoA thiolase, ACAT2, Acetyl CoA transferase-like protein, ACAT-2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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