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ACAT1 Monoclonal Antibody [PAT2C5A] (CPAB0463)

SKU:
CPAB0463
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT2C5A
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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ACAT1 Monoclonal Antibody [PAT2C5A] (CPAB0463)

The ACAT1 Polyclonal Antibody (CPAB0463) is a valuable tool for researchers studying ACAT1, an enzyme involved in cholesterol metabolism and important for cellular lipid homeostasis. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ACAT1 protein, this antibody enables researchers to detect and analyze ACAT1 expression in various cell types, making it ideal for studies in metabolic disorders, cardiovascular diseases, and lipid metabolism research.

ACAT1, also known as acyl-CoA:cholesterol acyltransferase 1, plays a crucial role in cholesterol esterification and the formation of lipid droplets, contributing to cellular lipid storage and energy metabolism. Dysregulation of ACAT1 has been implicated in various diseases, including atherosclerosis, obesity, and metabolic syndromes. Investigation into the function of ACAT1 is crucial for understanding its role in lipid metabolism and developing potential therapies for related disorders.

Product Name:ACAT1 Antibody
Product Sku:CPAB0463
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ACAT1 mAb, clone PAT2C5A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACAT1 protein.
Clone:PAT2C5A.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:
Isotype:IgG1
Background:Acetoacetyl-CoA thiolase (ACAT1) is an enzyme member of the membrane-bound acyltransferase family and Sterol o-acyltransferase subfamily. The ACAT1 enzyme catalyzes the reversible formation of acetoacetyl-CoA from 2 molecules of acetyl-CoA. ACAT1 plays a part in lipoprotein compilation and dietary cholesterol absorption. Added to its acyltransferase activity, ACAT1 acts as a ligase.
Synonyms:Acetyl-CoA acetyltransferase, mitochondrial, EC 2.3.1.9, Acetoacetyl-CoA thiolase, T2, ACAT1, ACAT, MAT, THIL.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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