The ACADS Polyclonal Antibody (CAB7230) is a valuable tool for research involving the ACADS protein, an enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It binds specifically to the ACADS protein, allowing for the detection and analysis of this key enzyme in various cell types.ACADS plays a crucial role in breaking down fatty acids for energy production, making it essential for cellular metabolism. Dysregulation of ACADS activity has been linked to metabolic disorders such as fatty acid oxidation disorders.
By studying the expression and function of ACADS using this antibody, researchers can gain insights into metabolic pathways and potential therapeutic targets for related diseases.With its high reactivity and specificity, the ACADS Polyclonal Antibody is an invaluable tool for studies in metabolic research, biochemistry, and molecular biology. Its ability to target the ACADS protein with precision makes it an essential component for understanding the role of this enzyme in health and disease.
Product Name:
ACADS Rabbit Polyclonal Antibody
SKU:
CAB7230
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ACADS (NP_000008.1).
This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
35
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACADS Rabbit pAb (CAB7230) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
