The ACADS Polyclonal Antibody (CAB0945) is a valuable tool for researchers studying ACADS, a key enzyme involved in fatty acid metabolism. This antibody, raised in rabbits, is highly specific to human ACADS and has been validated for use in Western blot applications. By binding to the ACADS protein, this antibody enables the detection and analysis of ACADS in various cell types, making it an essential component of studies in metabolic disorders, lipid metabolism, and related diseases.ACADS plays a crucial role in the breakdown of fatty acids for energy production, making it a target of interest in research on metabolic diseases such as fatty acid oxidation disorders and mitochondrial dysfunction.
By understanding the function and regulation of ACADS, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment. The ACADS Polyclonal Antibody is a reliable tool for exploring the role of ACADS in health and disease, opening up new possibilities for advancements in the field of metabolism research.
Product Name:
ACADS Rabbit Polyclonal Antibody
SKU:
CAB0945
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ACADS (NP_000008.1).
This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.
Purification Method:
Affinity purification
Gene ID:
35
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACADS Rabbit pAb (CAB0945) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
