ACADM Rabbit Polyclonal Antibody (CAB1873)
- SKU:
- CAB1873
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ACADM Rabbit Polyclonal Antibody |
SKU: | CAB1873 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1). |
Sequence: | MAAG FGRC CRVL RSIS RFHW RSQH TKAN RQRE PGLG FSFE FTEQ QKEF QATA RKFA REEI IPVA AEYD KTGE YPVP LIRR AWEL GLMN THIP ENCG GLGL GTFD ACLI SEEL AYGC TGVQ TAIE GNSL GQMP IIIA GNDQ QKKK YLGR MTEE PLMC AYCV TEPG AGSD VAGI KTKA EKKG DEYI INGQ KMWI TNGG KANW YFLL ARSD PDPK APAN KAFT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MCAD; ACAD1; MCADH; ACADM |
Positive Sample: | HT-29,HepG2,U-251MG,K-562,Mouse liver,Mouse kidney,Mouse brain,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 47kDa |
Observed MW: | 46kDa |
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 34 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |