The AcadL Polyclonal Antibody (CAB1266) is a vital tool for researchers studying AcadL, a key enzyme involved in fatty acid metabolism and energy production. This antibody, produced in rabbits, is highly specific to human samples and validated for use in Western blot applications. By binding to the AcadL protein, this antibody allows for precise detection and analysis in various cell types, making it an essential component in studies related to metabolism, energy regulation, and mitochondrial function.AcadL, also known as acyl-CoA dehydrogenase long chain, plays a crucial role in breaking down long-chain fatty acids for energy production in the mitochondria.
Dysregulation of AcadL activity has been linked to metabolic disorders, fatty acid oxidation disorders, and mitochondrial dysfunction. Therefore, gaining a better understanding of AcadL function is essential for developing targeted therapies for these conditions.Overall, the AcadL Polyclonal Antibody (CAB1266) is a valuable tool for researchers seeking to elucidate the role of AcadL in various physiological and pathological processes, paving the way for potential therapeutic advancements in metabolic diseases and mitochondrial disorders.
Product Name:
ACADL Rabbit Polyclonal Antibody
SKU:
CAB1266
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-210 of human ACADL (NP_001599.1).
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
Purification Method:
Affinity purification
Gene ID:
33
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ACADL Rabbit pAb (CAB1266) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
