The ACAD9 Polyclonal Antibody (CAB14121) is a valuable tool for researchers studying ACAD9, an essential enzyme involved in mitochondrial function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the ACAD9 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it ideal for investigations in biochemistry, metabolism, and mitochondrial diseases.ACAD9 is a key player in the mitochondrial electron transport chain, where it functions to catalyze the conversion of acyl-CoA to acylcarnitine. Mutations in the ACAD9 gene have been associated with a spectrum of disorders, including mitochondrial respiratory chain deficiencies and metabolic disorders.
By studying ACAD9 expression and function, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.Overall, the ACAD9 Polyclonal Antibody offers a reliable tool for investigating the role of ACAD9 in mitochondrial function and disease pathology. Its specificity and sensitivity make it a valuable asset for researchers seeking to deepen their understanding of metabolic processes and develop new strategies for addressing mitochondrial disorders.
Product Name:
ACAD9 Rabbit Polyclonal Antibody
SKU:
CAB14121
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACAD9 (NP_054768.2).
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
28976
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACAD9 antibody (CAB14121) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
