The ACAD8 Polyclonal Antibody is specifically designed for researchers studying ACAD8, an enzyme involved in fatty acid metabolism. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in Western blot applications. By binding to the ACAD8 protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in metabolism and metabolic disorders.ACAD8 is a crucial enzyme that plays a key role in breaking down fatty acids for energy production. Dysregulation of ACAD8 activity has been implicated in various metabolic disorders, making it a promising target for research into obesity, diabetes, and other metabolic diseases.
Understanding the function and regulation of ACAD8 is essential for developing targeted therapies to treat these conditions.Overall, the ACAD8 Polyclonal Antibody is a valuable tool for researchers investigating the role of ACAD8 in metabolism and metabolic disorders. Its high specificity and reliability make it a trusted choice for Western blot applications and other research techniques in the field of metabolism.
Product Name:
ACAD8 Polyclonal Antibody
SKU:
CAB23663
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant protein of human ACAD8.
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:2000 - 1:7000
Synonyms:
IBDH; ARC42; ACAD-8; ACAD8
Positive Sample:
Mouse liver,Rat kidney
Conjugate:
Unconjugated
Calculated MW:
45kDa
Observed MW:
43kDa
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
Purification Method:
Affinity purification
Gene ID:
27034
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ACAD8 Rabbit pAb (CAB23663) at 1:6000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
