The ACAD8 Polyclonal Antibody (PAC015248) is a specialized tool for researchers studying the ACAD8 protein, an enzyme involved in fatty acid metabolism. This antibody, derived from rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to ACAD8, researchers can accurately detect and analyze the protein in a variety of cell types, making it a valuable asset for studies in metabolic disorders and lipid metabolism.ACAD8, also known as Acyl-CoA Dehydrogenase Family Member 8, plays a crucial role in breaking down long-chain fatty acids for energy production. Dysregulation of ACAD8 has been linked to various metabolic disorders, making it a promising target for research into conditions such as fatty acid oxidation disorders and mitochondrial diseases.
By understanding the function and regulation of ACAD8, researchers can uncover potential therapeutic targets for these complex diseases.Overall, the ACAD8 Polyclonal Antibody (PAC015248) is a reliable tool for studying the role of ACAD8 in metabolic pathways and disease processes. Its specificity and sensitivity make it a valuable asset for research in biochemistry, metabolism, and genetic disorders. Unlock the potential of ACAD8 in your research with this high-quality antibody.
Antibody Name:
ACAD8 Antibody (PACO15248)
Antibody SKU:
PACO15248
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:15-1:50
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human ACAD8
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15248(ACAD8 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15248(ACAD8 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acid, or branch chained amino acid, The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid, valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
Synonyms:
acyl-CoA dehydrogenase family, member 8
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]
