The ACAA1 Polyclonal Antibody (CAB7422) is a valuable tool for researchers studying ACAA1, an enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ACAA1 protein, researchers can accurately detect and analyze ACAA1 expression in various cell types, making it an essential reagent for studies in metabolism and lipid biology.ACAA1 is a key enzyme in the beta-oxidation pathway, playing a crucial role in breaking down fatty acids for energy production. Dysregulation of ACAA1 has been linked to metabolic disorders, including obesity and fatty liver disease.
By studying the expression and activity of ACAA1, researchers can gain insights into the physiological and pathological processes underlying these conditions, potentially leading to the development of novel therapeutic strategies targeting lipid metabolism.Overall, the ACAA1 Polyclonal Antibody is a valuable resource for researchers interested in investigating the role of ACAA1 in metabolism and related diseases. Its high specificity and sensitivity make it an ideal tool for exploring the functions of this important enzyme and its potential implications for human health.
Product Name:
ACAA1 Rabbit Polyclonal Antibody
SKU:
CAB7422
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1).
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
30
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACAA1 antibody (CAB7422) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
