The ACAA1 Polyclonal Antibody (CAB14700) is a vital tool for researchers studying ACAA1, an enzyme involved in fatty acid metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the ACAA1 protein, researchers can effectively detect and analyze its expression in a variety of cell types, making this antibody ideal for studies in lipid metabolism and related diseases.ACAA1, also known as acetyl-CoA acyltransferase, plays a crucial role in beta-oxidation of fatty acids and ketone body metabolism.
Dysregulation of ACAA1 has been linked to metabolic disorders such as fatty acid oxidation defects and metabolic syndrome. By studying the function and expression of ACAA1, researchers can gain insights into the underlying mechanisms of these diseases and potentially identify new therapeutic targets for treatment.Overall, the ACAA1 Polyclonal Antibody is a valuable tool for researchers interested in unraveling the complexities of lipid metabolism and its implications for human health. Its specificity and reliability make it a key asset in advancing our understanding of ACAA1 and its role in metabolic diseases.
Product Name:
ACAA1 Rabbit Polyclonal Antibody
SKU:
CAB14700
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1).
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
30
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ACAA1 Rabbit pAb (CAB14700) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
