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AC1 Antibody (PACO34286)

SKU:
PACO34286
Product Type:
Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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AC1 Antibody (PACO34286)

The AC1 Antibody (PAC034286) is a polyclonal antibody specifically designed for research involving AC1, a key protein involved in [specific function]. This antibody, derived from [source], is highly reactive with [specific species] samples and has been validated for use in [specific applications]. It binds to the AC1 protein, enabling precise detection and analysis in [specific cell types], making it an essential tool for studies in [specific research areas].AC1, also known as [alternate name], plays a crucial role in [specific function or pathway] by [specific activity].

Its importance in [specific context] makes it a valuable target for research into diseases like [specific diseases]. Understanding the function of AC1 is essential for the development of therapies that target or modulate its activity in these contexts. This antibody provides researchers with a reliable tool for advancing knowledge in the field of [specific research area].

Antibody Name:AC1 Antibody (PACO34286)
Antibody SKU:PACO34286
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:African cassava mosaic virus
Immunogen:Recombinant African cassava mosaic virus Replication-associated protein (1-358AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
Synonyms:Replication-associated protein (Rep) (EC 2.7.7.-) (EC 3.1.21.-) (40.4 kDa protein) (Protein AC1) (Protein AL1)
UniProt Protein Function:Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:P14982
NCBI GenInfo Identifier:137408
NCBI Gene ID:
NCBI Accession:P14982.1
UniProt Secondary Accession:P14982
UniProt Related Accession:P14982
Molecular Weight:42.3 kDa
NCBI Full Name:Replication-associated protein
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Replication-associated protein
UniProt Synonym Protein Names:40.4 kDa protein; Protein AC1; Protein AL1
Protein Family:Replication-associated protein
UniProt Gene Name:AC1  
UniProt Entry Name:REP_CLVK

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