The ABLIM3 Polyclonal Antibody (CAB17643) is a valuable tool for research involving ABLIM3, a protein involved in cell adhesion and cytoskeletal organization. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically targeting the ABLIM3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.ABLIM3, also known as actin-binding LIM protein 3, plays a crucial role in organizing the actin cytoskeleton and regulating cell migration and adhesion.
Its importance in these processes makes it a promising target for research into diseases like cancer, where aberrant cell movement and adhesion play a critical role in metastasis. By studying the function of ABLIM3, researchers can gain valuable insights into the mechanisms underlying cancer progression and potentially develop targeted therapies to disrupt these processes.
Product Name:
ABLIM3 Rabbit Polyclonal Antibody
SKU:
CAB17643
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-520 of human ABLIM3 (NP_001287957.1).
This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients.
Purification Method:
Affinity purification
Gene ID:
22885
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ABLIM3 Rabbit pAb (CAB17643) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
