The ABLIM2 Polyclonal Antibody (CAB17792) is specifically designed for research involving ABLIM2, a protein involved in cell adhesion and actin binding. This antibody, generated in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot and immunofluorescence assays. By targeting the ABLIM2 protein, researchers can study its role in cellular processes and pathways related to cell adhesion, cytoskeletal organization, and signaling cascades.ABLIM2, also known as actin-binding LIM domain protein 2, is known to interact with actin filaments and play a role in maintaining cell structure and function.
Its involvement in cytoskeletal dynamics suggests potential implications in cell migration, adhesion, and signaling events. Research on ABLIM2 is particularly relevant in fields like cell biology, cancer research, and developmental biology, as abnormalities in actin dynamics can contribute to various disease states.By utilizing the ABLIM2 Polyclonal Antibody in research studies, scientists can gain valuable insights into the function and regulation of ABLIM2, paving the way for a better understanding of its role in cellular processes and potential therapeutic targets in diseases involving cytoskeletal abnormalities.
Product Name:
ABLIM2 Rabbit Polyclonal Antibody
SKU:
CAB17792
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 74-309 of human ABLIM2 (NP_115808.3).
Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in actin cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
84448
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using ABLIM2 Rabbit pAb (CAB17792) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
