The ABI2 Polyclonal Antibody (CAB14992) is a crucial tool for researchers studying ABI2, a protein known for its role in various cellular processes such as cell migration, adhesion, and cytoskeletal dynamics. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications.ABI2 is a key player in signaling pathways that control cell morphology and motility, making it a target of interest in cancer research and developmental biology. By detecting and quantifying ABI2 protein levels in different cell types, researchers can gain insights into its function and potential implications in disease development and progression.
With its ability to accurately detect ABI2 protein expression, this polyclonal antibody is a valuable tool for scientists conducting studies in cell biology, cancer biology, and drug discovery. By elucidating the role of ABI2 in various cellular processes, researchers can uncover new therapeutic targets and develop innovative strategies for combating diseases such as cancer and neurological disorders.
Product Name:
ABI2 Rabbit Polyclonal Antibody
SKU:
CAB14992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
Enables several functions, including SH3 domain binding activity; identical protein binding activity; and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction; positive regulation of cellular component organization; and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including filopodium tip; lamellipodium; and nucleoplasm. Part of SCAR complex. Is active in adherens junction. Colocalizes with actin filament.
Purification Method:
Affinity purification
Gene ID:
10152
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ABI2 Rabbit pAb (CAB14992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
