The ABHD6 Polyclonal Antibody (CAB23526) is a valuable tool for researchers studying ABHD6, an enzyme involved in lipid metabolism and signaling pathways. This antibody, raised in rabbits, has been validated for use in various applications, including Western blot and immunohistochemistry, and shows high specificity and sensitivity for detecting ABHD6 protein levels in human samples.ABHD6 plays a crucial role in the regulation of lipid metabolism, particularly in the hydrolysis of monoacylglycerols, which are important in cellular signaling processes. Dysregulation of ABHD6 has been implicated in various diseases, including metabolic disorders, neurodegenerative diseases, and cancer.
Understanding the function and regulation of ABHD6 is essential for developing targeted therapies for these conditions.With its high reactivity and specificity, the ABHD6 Polyclonal Antibody provides a reliable tool for researchers to investigate the role of ABHD6 in lipid metabolism and its potential implications in disease pathogenesis. Its use in research can help advance our understanding of ABHD6 function and aid in the development of novel therapeutic approaches in various disease settings.
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycerophosphate (BMP and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting.
Purification Method:
Affinity purification
Gene ID:
57406
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using ABHD6 Rabbit pAb (CAB23526) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
