The ABHD4 Polyclonal Antibody (CAB17751) is a valuable tool for researchers studying ABHD4, an enzyme involved in lipid metabolism and signaling pathways. This antibody, developed in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot assays. By targeting the ABHD4 protein, this antibody allows for the detection and analysis of ABHD4 expression in various cell types, making it a useful tool for investigations in biochemistry, cell biology, and lipid metabolism research.
ABHD4 is known to regulate lipid metabolism by hydrolyzing lipid substrates, thus playing a crucial role in maintaining lipid homeostasis and cell function. Dysregulation of ABHD4 has been implicated in various diseases, including metabolic disorders, neurodegenerative diseases, and cancer. By understanding the function and regulation of ABHD4, researchers can potentially develop new therapeutic strategies targeting lipid metabolism pathways for the treatment of these conditions.
Product Name:
ABHD4 Rabbit Polyclonal Antibody
SKU:
CAB17751
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 223-342 of human ABHD4 (NP_071343.2).
Predicted to enable lysophosphatidic acid acyltransferase activity and lysophospholipase activity. Predicted to be involved in N-acylphosphatidylethanolamine metabolic process; lipid homeostasis; and phosphatidic acid biosynthetic process. Predicted to act upstream of or within N-acylethanolamine metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in lipid droplet and mitochondrion.
Purification Method:
Affinity purification
Gene ID:
63874
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using ABHD4 Rabbit pAb (CAB17751) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
