The ABHD3 Polyclonal Antibody (PAC039202) is a valuable tool for researchers studying ABHD3, an enzyme involved in lipid metabolism and signaling pathways. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the ABHD3 protein, it allows for detection and analysis in a variety of cell types, making it an ideal choice for studies in biochemistry and cell biology.ABHD3 is known for its role in lipid metabolism and has been linked to various diseases, including metabolic disorders and cancer. Its involvement in lipid signaling pathways makes it a promising target for research focused on understanding the mechanisms underlying these conditions.
By investigating the function of ABHD3, researchers can gain insight into potential therapeutic strategies for addressing lipid-related diseases.Overall, the ABHD3 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of ABHD3 in lipid metabolism and associated diseases. Its high reactivity and specificity make it a reliable choice for Western blot applications, enabling detailed analysis of ABHD3 expression and function in cellular processes.
Immunohistochemistry of paraffin-embedded human lung tissue using PACO39202 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO39202 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids.
ABHD3: a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]Protein type: EC 3.1.1.-; Membrane protein, integral; HydrolaseChromosomal Location of Human Ortholog: 18q11.2Cellular Component: plasma membraneMolecular Function: phospholipase A1 activity; phospholipase A2 activityBiological Process: phosphatidylcholine biosynthetic process; phosphatidylcholine metabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]
