Description
ABHD14B Antibody (PACO38986)
The ABHD14B Polyclonal Antibody (PAC038986) is an essential tool for research involving ABHD14B, a protein involved in lipid metabolism and cellular signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ABHD14B protein, this antibody enables precise detection and analysis in various cell types, making it ideal for studies related to lipid biology and metabolic disorders.ABHD14B, a member of the AB hydrolase domain-containing protein family, is known for its role in lipid metabolism, including the breakdown of lipid molecules and regulation of lipid signaling pathways.
Its involvement in cellular processes related to lipid homeostasis makes it a key target for research in fields such as metabolism, obesity, and neurodegenerative diseases. Understanding the function of ABHD14B is crucial for advancing knowledge in lipid biology and developing therapeutic approaches for lipid-related disorders.Overall, the ABHD14B Polyclonal Antibody (PAC038986) offers researchers a valuable tool for investigating the role of ABHD14B in cellular functions and metabolic pathways. Its high specificity and reactivity make it a reliable asset for studies aiming to unravel the complexities of lipid metabolism and its implications in various disease states.
Antibody Name: | ABHD14B Antibody (PACO38986) |
Antibody SKU: | PACO38986 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Protein ABHD14B protein (2-210AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: ABHD14B antibody at 16µg/ml. Lane 1: Mouse small intestine tissue. Lane 2: Mouse spleen tissue. Lane 3: Mouse liver tissue. Lane 4: Mouse lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 23, 19 kDa. Observed band size: 23 kDa. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO38986 at dilution of 1:100. |
Background: | Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription. |
Synonyms: | Protein ABHD14B (EC 3.-.-.-) (Alpha/β hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) (CCG1-interacting factor B), ABHD14B, CIB |
UniProt Protein Function: | ABHD14B: Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription. Belongs to the AB hydrolase superfamily. ABHD14 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.-.-.-; Hydrolase Chromosomal Location of Human Ortholog: 3p21.2 Cellular Component: cytoplasm; nucleolus; cytosol; nucleus Molecular Function:protein binding; hydrolase activity Biological Process: metabolic process; positive regulation of transcription from RNA polymerase II promoter |
UniProt Code: | Q96IU4 |
NCBI GenInfo Identifier: | 34222621 |
NCBI Gene ID: | 84836 |
NCBI Accession: | Q96IU4.1 |
UniProt Secondary Accession: | Q96IU4,Q86VK8, Q8N8W5, |
UniProt Related Accession: | Q96IU4 |
Molecular Weight: | 210 |
NCBI Full Name: | Alpha/beta hydrolase domain-containing protein 14B |
NCBI Synonym Full Names: | abhydrolase domain containing 14B |
NCBI Official Symbol: | ABHD14BÂ Â |
NCBI Official Synonym Symbols: | CIB; HEL-S-299Â Â |
NCBI Protein Information: | alpha/beta hydrolase domain-containing protein 14B; CCG1-interacting factor B; epididymis secretory protein Li 299; cell cycle gene 1-interacting factor B; abhydrolase domain-containing protein 14B |
UniProt Protein Name: | Alpha/beta hydrolase domain-containing protein 14B |
UniProt Synonym Protein Names: | CCG1-interacting factor B |
Protein Family: | Protein |
UniProt Gene Name: | ABHD14BÂ Â |
UniProt Entry Name: | ABHEB_HUMAN |