The ABHD11 Polyclonal Antibody (PACO00355) is a valuable tool for researchers studying ABHD11, a protein involved in lipid metabolism and cellular signaling pathways. This antibody, raised in rabbits, is highly specific for human ABHD11 and has been validated for use in various experimental applications, including Western blot and immunohistochemistry.ABHD11, also known as alpha/beta-hydrolase domain-containing protein 11, plays a vital role in regulating lipid metabolism and cellular processes related to lipid signaling. Dysregulation of ABHD11 has been implicated in various diseases, making it a promising target for therapeutic intervention.
By using the ABHD11 Polyclonal Antibody, researchers can accurately detect and analyze ABHD11 protein levels in different cell types, facilitating investigation into its function in metabolic disorders, cancer, and other pathological conditions.Overall, the ABHD11 Polyclonal Antibody offers high specificity and sensitivity for detecting ABHD11 protein, making it an essential tool for researchers interested in elucidating the role of ABHD11 in cellular metabolism and disease pathogenesis.
Antibody Name:
ABHD11 Antibody
Antibody SKU:
PACO00355
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human ABHD11.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ABHD11; WBSCR21; PP1226; Abhydrolase domain-containing protein 11; Williams-Beuren syndrome chromosomal region 21 protein
UniProt Protein Function:
ABHD11: ABHD11 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the AB hydrolase superfamily. 5 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.-.-.-; HydrolaseChromosomal Location of Human Ortholog: 7q11.23Molecular Function: hydrolase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]
