The ABHD10 Polyclonal Antibody (PAC053174) is a valuable tool for researchers studying ABHD10, an enzyme involved in lipid metabolism and signaling pathways. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ABHD10 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in biochemistry and cell biology.ABHD10 is known for its role in lipid metabolism, specifically in the hydrolysis of lipid esters. Dysregulation of ABHD10 has been linked to various metabolic disorders, making it a promising target for therapeutic interventions.
Understanding the function and regulation of ABHD10 is essential for developing treatments for conditions such as obesity, diabetes, and cardiovascular disease.Overall, the ABHD10 Polyclonal Antibody (PAC053174) offers researchers a reliable tool for investigating the role of ABHD10 in lipid metabolism and its potential as a therapeutic target for metabolic disorders. Its specificity and sensitivity make it an invaluable resource for advancing research in this field.
Antibody Name:
ABHD10 Antibody (PACO53174)
Antibody SKU:
PACO53174
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Mycophenolic acid, acyl-glucuronide esterase, mitochondrial protein (113-214AA)
Immunohistochemistry analysis of human small intestine tissue using PACO53174 at dilution of 1:100.
Background:
Catalyzes the deglucuronidation of mycophenolic acid, acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate.
Synonyms:
Mycophenolic acid, acyl-glucuronide esterase, mitochondrial (EC 3.1.1.93) (Alpha/β hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10), ABHD10
UniProt Protein Function:
Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate.
UniProt Protein Details:
NCBI Summary:
This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
