ABCG5 Rabbit Polyclonal Antibody (CAB8589)
- SKU:
- CAB8589
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ABCG5 Rabbit Polyclonal Antibody |
SKU: | CAB8589 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human ABCG5 (NP_071881.1). |
Sequence: | TLPM VPFK TKDS PGVF SKLG VLLR RVTR NLVR NKLA VITR LLQN LIMG LFLL FFVL RVRS NVLK GAIQ DRVG LLYQ FVGA TPYT GMLN AVNL FPVL RAVS D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | STSL; STSL2; ABCG5 |
Positive Sample: | HL-60 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 73kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.
Purification Method: | Affinity purification |
Gene ID: | 64240 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |