The ABCG4 Polyclonal Antibody (CAB14596) is a valuable tool for researchers studying the ABCG4 protein, a member of the ATP-binding cassette (ABC) transporter family known for its role in lipid transportation and metabolism. This antibody, produced in rabbits, has been carefully validated for use in Western blot applications and exhibits high reactivity with human samples.ABCG4 is involved in intracellular lipid transport and has been linked to various physiological processes, including cholesterol homeostasis and lipid metabolism. Dysregulation of ABCG4 has been implicated in lipid disorders, neurodegenerative diseases, and cardiovascular conditions.
By targeting the ABCG4 protein, researchers can investigate its function in lipid transport pathways and explore its potential role in disease development.The ABCG4 Polyclonal Antibody (CAB14596) offers a reliable tool for detecting and analyzing ABCG4 protein expression in a variety of cell types, facilitating research in lipid biology, metabolic disorders, and neurodegenerative diseases. With its high specificity and sensitivity, this antibody is an essential asset for scientists seeking to unravel the complexities of ABCG4 biology and its implications for human health.
Product Name:
ABCG4 Rabbit Polyclonal Antibody
SKU:
CAB14596
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 270-370 of human ABCG4 (NP_071452.2).
The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1.
Purification Method:
Affinity purification
Gene ID:
64137
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ABCG4 Rabbit pAb (CAB14596) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
