The ABCG1 Rabbit Monoclonal Antibody (CAB17907) is a valuable tool for researchers studying ABCG1, a protein involved in cholesterol homeostasis and lipid transport. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting ABCG1 in human samples, making it ideal for use in Western blot applications. By targeting the ABCG1 protein, this antibody enables researchers to analyze and quantify its expression in various cell types, aiding in the investigation of lipid metabolism and related diseases such as atherosclerosis and metabolic disorders.
ABCG1 is a key player in cholesterol efflux and transport, crucial for maintaining cellular lipid balance and preventing the development of cardiovascular diseases. Dysregulation of ABCG1 has been linked to increased cholesterol accumulation and inflammation, highlighting its significance in lipid metabolism and its potential as a therapeutic target. By utilizing the ABCG1 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function of ABCG1 and its role in lipid-related disorders, paving the way for the development of novel treatment strategies.
Product Name:
ABCG1 Rabbit Monoclonal Antibody
SKU:
CAB17907
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABCG1 (NP_004906.3).
Sequence:
LLKG ISGK FNSG ELVA IMGP SGAG KSTL MNIL AGYR ETGM KGAV LING LPRD LRCF RKVS CYIM QDDM LLPH LTVQ EAMM VSAH LKLQ EKDE GRRE MVKE I
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
ABC8; WHITE1; ABCG1
Positive Sample:
Hep G2,A-549,HeLa,Mouse liver,Mouse thymus,Rat spleen
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
Purification Method:
Affinity purification
Gene ID:
9619
Clone Number:
ARC0336
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ABCG1 antibody (CAB17907) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
