null

ABCD4 Rabbit Polyclonal Antibody (CAB17523)

SKU:
CAB17523
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABCD4 Rabbit Polyclonal Antibody
SKU:CAB17523
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-280 of human ABCD4 (NP_005041.1).
Sequence:DQFT CNLL YVSW RKDL TEHL HRLY FRGR AYYT LNVL RDDI DNPD QRIS QDVE RFCR QLSS MASK LIIS PFTL VYYT YQCF QSTG WLGP VSIF GYFI LGTV VNKT LMGP IVMK LVHQ EKLE GDFR FKHM QIRV NAEP AAFY RAGH VEHM RTDR RLQR LLQT QREL MSKE LWLY IGIN TFDY L
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188; ABCD4
Positive Sample:MCF7
Conjugate:Unconjugated
Cellular Localization:peroxisome
Calculated MW:69kDa
Observed MW:72kDa

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants.

Purification Method:Affinity purification
Gene ID:5826
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from MCF7 cells, using ABCD4 Rabbit pAb (CAB17523) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

Related Products