PMP70/ABCD3 Rabbit Polyclonal Antibody (CAB18177)
- SKU:
- CAB18177
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | PMP70/ABCD3 Rabbit Polyclonal Antibody |
SKU: | CAB18177 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-475 of human PMP70/ABCD3 (NP_002849.1). |
Sequence: | LSHP RHLK STHS ELLE DYYQ SGRM LLRM SQAL GRIV LAGR EMTR LAGF TARI TELM QVLK DLNH GKYE RTMV SQQE KGIE GVQV IPLI PGAG EIII ADNI IKFD HVPL ATPN GDVL IRDL NFEV RSGA NVLI CGPN |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ZWS2; ABC43; CBAS5; PMP70; PXMP1; PMP70/ABCD3 |
Positive Sample: | HeLa,HepG2,Mouse liver,Mouse kidney,Rat liver |
Cellular Localization: | cytosol, mitochondrion, peroxisomal matrix, peroxisome |
Calculated MW: | 75kDa |
Observed MW: | 70kDa |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5825 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |