ABCD1 / ALD Monoclonal Antibody (CAB23569)
- SKU:
- CAB23569
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
ABCD1 / ALD Monoclonal Antibody (CAB23569)
The ABCD1-ALD Monoclonal Antibody is a cutting-edge tool for research in X-linked adrenoleukodystrophy (ALD), a rare genetic disorder that affects the nervous system and adrenal glands. This antibody, created using advanced technology, specifically targets the ABCD1 protein, which is mutated in individuals with ALD.By binding to ABCD1, this monoclonal antibody allows for precise detection and analysis of the protein in various sample types, facilitating research on the molecular mechanisms underlying ALD. Its high specificity and sensitivity make it a valuable tool for studies aimed at understanding the pathogenesis of ALD and developing new therapies for this devastating condition.
Furthermore, the ABCD1-ALD Monoclonal Antibody has been rigorously validated for use in techniques such as immunohistochemistry and flow cytometry, providing researchers with reliable and reproducible results. Its versatility and reliability make it an indispensable reagent for investigators working in the fields of neurology, genetics, and rare diseases.Overall, the ABCD1-ALD Monoclonal Antibody offers a powerful means to advance our knowledge of ALD and ultimately improve diagnosis and treatment options for individuals affected by this challenging disorder.
| Product Name: | ABCD1 / ALD Monoclonal Antibody |
| Product Code: | CAB23569 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC3076 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, HeLa, NIH/3T3 |
| Cellular Location: | Multi-pass membrane protein, Peroxisome membrane |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
| Immunogen: | Recombinant protein of human ABCD1 / ALD. |
| Sequence: | Email for sequence |
| Synonyms: | ALD, AMN, ALDP, ABC42 |
| Calculated MW: | 83kDa |
| Observed MW: | 83kDa |
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