MRP4/ABCC4 Rabbit Polyclonal Antibody (CAB2198)
- SKU:
- CAB2198
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | MRP4/ABCC4 Rabbit Polyclonal Antibody |
SKU: | CAB2198 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1067-1325 of human MRP4/ABCC4 (NP_005836.2). |
Sequence: | SQEK VGIV GRTG AGKS SLIS ALFR LSEP EGKI WIDK ILTT EIGL HDLR KKMS IIPQ EPVL FTGT MRKN LDPF NEHT DEEL WNAL QEVQ LKET IEDL PGKM DTEL AESG SNFS VGQR QLVC LARA ILRK NQIL IIDE ATAN VDPR TDEL IQKK IREK FAHC TVLT IAHR LNTI IDSD KIMV LDSG RLKE YDEP YVLL QNKE SLFY KMVQ QLGK AEAA ALTE TAKQ VYFK RNYP HIGH TDHM VTNT SNGQ PSTL TIFE TAL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | MRP4; MOATB; MOAT-B; MRP4/ABCC4 |
Positive Sample: | HeLa,HeLa Cytoplasm extracts,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 150kDa |
Observed MW: | 140-200kDa |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 10257 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |