The ABCC13 Polyclonal Antibody (PACO6216) is a valuable tool for researchers studying the ABCC13 protein, a member of the ATP-binding cassette transporters family implicated in drug resistance and transport processes. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications. By targeting the ABCC13 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for investigations in pharmacology and drug resistance mechanisms.ABCC13, also known as multidrug resistance protein 10 (MRP10), plays a crucial role in mediating the efflux of various compounds from cells, thereby impacting drug resistance and cellular detoxification processes.
Its involvement in drug transport mechanisms makes it a valuable target for research into cancer therapy, drug development, and pharmacokinetics. Understanding the function of ABCC13 is essential for developing strategies to overcome drug resistance and improve the efficacy of chemotherapy treatments.Overall, the ABCC13 Polyclonal Antibody (PACO6216) offers researchers a reliable tool for studying the ABCC13 protein and its role in drug resistance mechanisms, making it a valuable asset in the fields of pharmacology and cancer research.
Antibody Name:
ABCC13 Antibody (PACO06216)
Antibody SKU:
PACO06216
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human ABCC13.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of HELA cells using ABCC13 Polyclonal Antibody.
Western Blot analysis of HT29 cells using ABCC13 Polyclonal Antibody.
Synonyms:
ABCC13; C21orf73; PRED6; Putative ATP-binding cassette sub-family C member 13
UniProt Protein Function:
ABCC13: a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]Protein type: Transporter; Membrane protein, integral; Hydrolase; Transporter, ABC family; Membrane protein, multi-passChromosomal Location of Human Ortholog: 21q11.2Cellular Component: integral to membraneMolecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP bindingBiological Process: transmembrane transport
