ABCB8 Rabbit Polyclonal Antibody (CAB2653)
- SKU:
- CAB2653
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | ABCB8 Rabbit Polyclonal Antibody |
SKU: | CAB2653 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 469-718 of human ABCB8 (NP_009119.2). |
Sequence: | GFEV LKDF TLTL PPGK IVAL VGQS GGGK TTVA SLLE RFYD PTAG VVML DGRD LRTL DPSW LRGQ VVGF ISQE PVLF GTTI MENI RFGK LEAS DEEV YTAA REAN AHEF ITSF PEGY NTVV GERG TTLS GGQK QRLA IARA LIKQ PTVL ILDE ATSA LDAE SERV VQEA LDRA SAGR TVLV IAHR LSTV RGAH CIVV MADG RVWE AGTH EELL KKGG LYAE LIRR QALD APRT AAPP PKKP EGPR SHQH KS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | MABC1; M-ABC1; MITOSUR; EST328128; ABCB8 |
Positive Sample: | MCF7,Jurkat,HepG2,HeLa,Mouse heart,Mouse skin,Mouse kidney,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane, Multi-pass membrane protein. |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 11194 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |