ABCB4 Rabbit Polyclonal Antibody (CAB9835)
- SKU:
- CAB9835
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ABCB4 Rabbit Polyclonal Antibody |
SKU: | CAB9835 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human ABCB4 (NP_061337.1). |
Sequence: | MDLE AAKN GTAW RPTS AEGD FELG ISSK QKRK KTKT VKMI GVLT LFRY SDWQ DKLF MSLG TIMA IAHG SGLP LMMI VFGE MTDK FVDT AGNF SFPV NFSL SLLN PGKI LE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GBD1; ICP3; MDR2; MDR3; PGY3; ABC21; MDR2/3; PFIC-3; ABCB4 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Apical cell membrane, Cell membrane, Cytoplasm, Cytoplasmic vesicle, Membrane raft, Multi-pass membrane protein, clathrin-coated vesicle. |
Calculated MW: | 142kDa |
Observed MW: | 144kDa |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Purification Method: | Affinity purification |
Gene ID: | 5244 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |