ABCA7 Rabbit Polyclonal Antibody (CAB18280)
- SKU:
- CAB18280
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | ABCA7 Rabbit Polyclonal Antibody |
SKU: | CAB18280 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2010-2146 of human ABCA7 (NP_061985.2). |
Sequence: | QHLK GRFA AGHT LTLR VPAA RSQP AAAF VAAE FPGA ELRE AHGG RLRF QLPP GGRC ALAR VFGE LAVH GAEH GVED FSVS QTML EEVF LYFS KDQG KDED TEEQ KEAG VGVD PAPG LQHP KRVS QFLD DPST AETV L |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | AD9; ABCX; ABCA-SSN; ABCA7 |
Positive Sample: | Rat brain |
Cellular Localization: | cell surface, endoplasmic reticulum, glial cell projection, Golgi apparatus, phagocytic cup, plasma membrane, ruffle membrane |
Calculated MW: | 234kDa |
Observed MW: | 260kDa |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system.
Purification Method: | Affinity purification |
Gene ID: | 10347 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |