The ABCA6 Polyclonal Antibody (CAB3191) is a specialized tool for researchers studying ABCA6, a member of the ATP-binding cassette (ABC) transporter family known for its role in lipid transport and homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Known for its involvement in lipid metabolism, ABCA6 has been linked to various diseases, including atherosclerosis, diabetes, and Alzheimer's disease. By specifically binding to the ABCA6 protein, this antibody allows for accurate detection and analysis of ABCA6 expression in different cell types, making it an invaluable resource for studies in lipid biology and disease pathology.
Understanding the function and regulation of ABCA6 is essential for uncovering its potential as a therapeutic target in lipid-related disorders. The ABCA6 Polyclonal Antibody provides researchers with a reliable tool for investigating the molecular mechanisms underlying ABCA6-mediated lipid transport and metabolism, paving the way for the development of novel treatment strategies for associated diseases.
Product Name:
ABCA6 Rabbit Polyclonal Antibody
SKU:
CAB3191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 690-828 of human ABCA6 (NP_525023.2).
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in Golgi membrane; nucleoplasm; and plasma membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in tail. Orthologous to human ABCA6 (ATP binding cassette subfamily A member 6).
Purification Method:
Affinity purification
Gene ID:
76184
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB3191) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
